Tositumomab

Revision as of 17:01, 12 December 2010 by David Canner (Talk | contribs)

(diff) ←Older revision | Current revision (diff) | Newer revision→ (diff)

Anti-CD20 Monoclonal Antibody Pharmacokinetics ^[1]
Parameter	Tositumomab	Ofatumumab	Rituximab	Ibritumomab
T_max (hr)	Tositumomab	7.6	Rituximab	Ibritumomab
C_max (ng/ml)	Tositumomab	167000	205800	67000
Bioavailability (%)	Tositumomab	Ofatumumab	Rituximab	Ibritumomab
T_1/2 (hr)	64.8	68	206	108
AUC (ng/ml/hr)	Tositumomab	32939000	Rituximab	17000
Clearance (L/h)	.078	.017	.009	Ibritumomab
IC₅₀ (nM)	Tositumomab	Ofatumumab	Rituximab	Ibritumomab
Dosage	Tositumomab	500 mg (4th Infusion)	325 mg/m² (4th Infusion)	Ibritumomab
Metabolism	Tositumomab	Ofatumumab	Rituximab	Ibritumomab

Proteopedia Page Contributors and Editors (what is this?)