Chymotrypsin Inhibitor

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Image:4wbc.png
Crystal Structure of Chymotrypsin Inhibitor 4wbc

Template:STRUCTURE 4wbc

Chymotrypsin Inhibitors are serine proteinase inhibitors of chymotrypsin. They are classified by numbers: CI-1, CI-2, CI-3. The images at the left and at the right correspond to one representative Chymotrypsin Inhibitor, i.e. the crystal structure of Chymotrypsin Inhibitor from Phosphocarpus tetragonolobus (4wbc).

Contents

3D Structures of Chymotrypsin Inhibitor

CI-1

2jzm – CI-1 fragment – Nicotiana alata – NMR 1eai – CI-1+elastase - pig


CI-2

1y1k, 1y33, 1y34, 1y3b, 1y3c, 1y3d, 1y3f, 1y48, 1y4a, 1y4d, 1tm1, 1tm3, 1tm4, 1tm5, 1tm7, 1tmg, 1to1, 1to2, 1lw6 – BaCI-2 (mutant)+subtilisin – Bacillus amyloliquefaciens 2sni - BaCI-2+subtilisin 1ciq, 1cir– HvCI-2 fragments – Hordeum vulgare 1coa, 1ypa, 1ypb, 1ypc – HvCI-2 (mutant) 1cis - HvCI-2+subtilisin helix – NMR 3ci2 - HvCI-2 – NMR 2ci2 - HvCI-2


CI-3

3i2a, 3i2x, 2bea, 2beb, 2esu, 2et2, 1xg6, 1fmz, 1fn0, 1eyl – PtCI-3 (mutant) – Phosphocarpus tetragonolobus 4wbc, 2wbc, 1wbc - PtCI-3 2qyi – CI-3 (mutant)+cationic trypsin – cow

1ccv – CI –Apis mellifera - NMR

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Michal Harel, Alexander Berchansky, Joel L. Sussman

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