2xti

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Image:2xti.jpg

Template:STRUCTURE 2xti

ASPARAGINYL-TRNA SYNTHETASE FROM BRUGIA MALAYI COMPLEXED WITH ATP:MG AND L-ASP-BETA-NOH ADENYLATE:PPI:MG

Template:ABSTRACT PUBMED 21134380

About this Structure

2XTI is a 2 chains structure with sequences from Brugia malayi. Full crystallographic information is available from OCA.

Reference

  • Crepin T, Peterson F, Haertlein M, Jensen D, Wang C, Cusack S, Kron M. A Hybrid Structural Model of the Complete Brugia malayi Cytoplasmic Asparaginyl-tRNA Synthetase. J Mol Biol. 2010 Dec 4. PMID:21134380 doi:10.1016/j.jmb.2010.11.049
  • Sukuru SC, Crepin T, Milev Y, Marsh LC, Hill JB, Anderson RJ, Morris JC, Rohatgi A, O'Mahony G, Grotli M, Danel F, Page MG, Hartlein M, Cusack S, Kron MA, Kuhn LA. Discovering new classes of Brugia malayi asparaginyl-tRNA synthetase inhibitors and relating specificity to conformational change. J Comput Aided Mol Des. 2006 Mar;20(3):159-78. Epub 2006 Apr 28. PMID:16645791 doi:10.1007/s10822-006-9043-5

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