3oy3
From Proteopedia
Crystal structure of ABL T315I mutant kinase domain bound with a DFG-out inhibitor AP24589
Template:ABSTRACT PUBMED 21118377
About this Structure
3OY3 is a 2 chains structure with sequences from Mus musculus. Full crystallographic information is available from OCA.
Reference
- Zhou T, Commodore L, Huang WS, Wang Y, Thomas M, Keats J, Xu Q, Rivera VM, Shakespeare WC, Clackson T, Dalgarno DC, Zhu X. Structural Mechanism of the Pan-BCR-ABL Inhibitor Ponatinib (AP24534): Lessons for Overcoming Kinase Inhibitor Resistance. Chem Biol Drug Des. 2011 Jan;77(1):1-11. doi:, 10.1111/j.1747-0285.2010.01054.x. Epub 2010 Nov 30. PMID:21118377 doi:10.1111/j.1747-0285.2010.01054.x
Page seeded by OCA on Wed Dec 15 08:44:23 2010
Categories: Mus musculus | Non-specific protein-tyrosine kinase | Clackson, T. | Commodore, L. | Dalgarno, D C. | Huang, W S. | Keats, J. | Rivera, V. | Shakespeare, W C. | Thomas, M. | Wang, Y. | Xu, Q. | Zhou, T. | Zhu, X. | Atp binding | Phosphorylation | Phosphotransferase | Protein kinase two-domain fold | Protein-inhibitor complex | Transferase-transferase inhibitor complex
