3mh2

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Image:3mh2.png

Template:STRUCTURE 3mh2

Mutagenesis of p38 MAP kinase establishes key roles of Phe169 in function and structural dynamics and reveals a novel DFG-out state

Template:ABSTRACT PUBMED 17441692

About this Structure

3MH2 is a 1 chain structure with sequence from Homo sapiens. This structure supersedes the now removed PDB entry 2pto. Full crystallographic information is available from OCA.

Reference

  • Bukhtiyarova M, Karpusas M, Northrop K, Namboodiri HV, Springman EB. Mutagenesis of p38alpha MAP kinase establishes key roles of Phe169 in function and structural dynamics and reveals a novel DFG-OUT state. Biochemistry. 2007 May 15;46(19):5687-96. Epub 2007 Apr 19. PMID:17441692 doi:10.1021/bi0622221

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