3nmq

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Image:3nmq.jpg

Template:STRUCTURE 3nmq

Hsp90b N-terminal domain in complex with EC44, a pyrrolo-pyrimidine methoxypyridine inhibitor

Template:ABSTRACT PUBMED 21131419

About this Structure

3NMQ is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Yun TJ, Harning EK, Giza K, Rabah D, Li P, Arndt JW, Luchetti D, Biamonte MA, Shi J, Lundgren K, Manning A, Kehry MR. EC144, a Synthetic Inhibitor of Heat Shock Protein 90, Blocks Innate and Adaptive Immune Responses in Models of Inflammation and Autoimmunity. J Immunol. 2011 Jan 1;186(1):563-75. Epub 2010 Dec 3. PMID:21131419 doi:10.4049/jimmunol.1000222

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