3nux

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Image:3nux.jpg

Template:STRUCTURE 3nux

CDK6 (monomeric) in complex with inhibitor

Template:ABSTRACT PUBMED 21038853

About this Structure

3NUX is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Cho YS, Borland M, Brain C, Chen CH, Cheng H, Chopra R, Chung K, Groarke J, He G, Hou Y, Kim S, Kovats S, Lu Y, O'Reilly M, Shen J, Smith T, Trakshel G, Vogtle M, Xu M, Xu M, Sung MJ. 4-(Pyrazol-4-yl)-pyrimidines as selective inhibitors of cyclin-dependent kinase 4/6. J Med Chem. 2010 Nov 25;53(22):7938-57. Epub 2010 Nov 1. PMID:21038853 doi:10.1021/jm100571n

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