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2zvt
From Proteopedia
Contents |
Cys285Ser mutant PPARgamma ligand-binding domain complexed with 15-deoxy-delta12,14-prostaglandin J2
Template:ABSTRACT PUBMED 19101554
About this Structure
2zvt is a 2 chain structure of Peroxisome Proliferator-Activated Receptors with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Waku T, Shiraki T, Oyama T, Morikawa K. Atomic structure of mutant PPARgamma LBD complexed with 15d-PGJ2: novel modulation mechanism of PPARgamma/RXRalpha function by covalently bound ligands. FEBS Lett. 2009 Jan 22;583(2):320-4. Epub 2008 Dec 26. PMID:19101554 doi:10.1016/j.febslet.2008.12.017
Categories: Homo sapiens | Morikawa, K. | Oyama, T. | Shiraki, T. | Waku, T. | Activator | Alternative splicing | Anti parallel helix sandwich | Diabetes mellitus | Disease mutation | Dna-binding | Metal-binding | Nucleus | Obesity | Phosphoprotein | Polymorphism | Receptor | Transcription | Transcription regulation | Zinc | Zinc-finger
