Template:STRUCTURE 1b41

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1b41, resolution 2.76Å ()

Sites:

, , and

Ligands:

, ,

Gene:

ACHE (Homo sapiens)

Activity:

Acetylcholinesterase, with EC number 3.1.1.7

Structural annotation:
Resources:	CATH : 1B41A00, 1B41B00 InterPro : Ipr014788, Ipr000997, Ipr002018 Pfam : PF00135 SCOP : d1b41a_, d1b41b_ UniProt : P22303, P0C1Z0

Functional annotation:
Cellular component:	extracellular region membrane basal lamina cell junction synapse Golgi apparatus perinuclear region of cytoplasm
Biological process:	cell proliferation osteoblast development response to wounding DNA replication cell adhesion amyloid precursor protein metabolic process acetylcholine catabolic process in synaptic cleft positive regulation of protein secretion acetylcholine catabolic process synaptogenesis negative regulation of synaptic transmission, cholinergic neurotransmitter catabolic process nervous system development muscle development
Molecular function:	protein homodimerization activity collagen binding hydrolase activity acetylcholinesterase activity serine hydrolase activity acetylcholine binding cholinesterase activity beta-amyloid binding laminin-1 binding

Evolutionary conservation:

Toggle Conservation Colors:

Rows = identical sequences:

Further Information:

Explanation,
Complete Results at ConSurfDB

Resources:

FirstGlance, OCA, PDBsum, RCSB

Coordinates:

save as pdb, mmCIF, xml

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