2obf

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Template:STRUCTURE 2obf

Contents 1 Structure of K57A hPNMT with inhibitor 3-Hydroxymethyl-7-(N-4-chlorophenylaminosulfonyl)-THIQ and AdoHcy (SAH) 2 About this Structure 3 See Also 4 Reference

Structure of K57A hPNMT with inhibitor 3-Hydroxymethyl-7-(N-4-chlorophenylaminosulfonyl)-THIQ and AdoHcy (SAH)

Template:ABSTRACT PUBMED 17845018

About this Structure

2obf is a 2 chain structure of Phenylethanolamine N-methyltransferase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

• Phenylethanolamine N-methyltransferase

Reference

• Gee CL, Drinkwater N, Tyndall JD, Grunewald GL, Wu Q, McLeish MJ, Martin JL. Enzyme adaptation to inhibitor binding: a cryptic binding site in phenylethanolamine N-methyltransferase. J Med Chem. 2007 Oct 4;50(20):4845-53. Epub 2007 Sep 11. PMID:17845018 doi:10.1021/jm0703385