1gj4

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Image:1gj4.png

Template:STRUCTURE 1gj4

Contents

SELECTIVITY AT S1, H2O DISPLACEMENT, UPA, TPA, SER190/ALA190 PROTEASE, STRUCTURE-BASED DRUG DESIGN

Template:ABSTRACT PUBMED 11731301

About this Structure

1gj4 is a 3 chain structure of Hirudin with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  • Katz BA, Sprengeler PA, Luong C, Verner E, Elrod K, Kirtley M, Janc J, Spencer JR, Breitenbucher JG, Hui H, McGee D, Allen D, Martelli A, Mackman RL. Engineering inhibitors highly selective for the S1 sites of Ser190 trypsin-like serine protease drug targets. Chem Biol. 2001 Nov;8(11):1107-21. PMID:11731301

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