2qu4

From Proteopedia

Revision as of 10:51, 23 January 2008 by OCA (Talk | contribs)
(diff) ←Older revision | Current revision (diff) | Newer revision→ (diff)
Jump to: navigation, search
Image:2qu4.jpg

2qu4

Drag the structure with the mouse to rotate

Model for Bacterial ParM Filament

Overview

Bacterial ParM is a homolog of eukaryotic actin and is involved in moving, plasmids so that they segregate properly during cell division. Using, cryo-EM and three-dimensional reconstruction, we show that ParM filaments, have a different structure from F-actin, with very different, subunit-subunit interfaces. These interfaces result in the helical, handedness of the ParM filament being opposite to that of F-actin. Like, F-actin, ParM filaments have a variable twist, and we show that this, involves domain-domain rotations within the ParM subunit. The present, results yield new insights into polymorphisms within F-actin, as well as, the evolution of polymer families.

About this Structure

2QU4 is a Single protein structure of sequence from Escherichia coli. Full crystallographic information is available from OCA.

Reference

The structure of bacterial ParM filaments., Orlova A, Garner EC, Galkin VE, Heuser J, Mullins RD, Egelman EH, Nat Struct Mol Biol. 2007 Oct;14(10):921-6. Epub 2007 Sep 16. PMID:17873883

Page seeded by OCA on Wed Jan 23 12:51:20 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2qu4"
Personal tools