3bel
From Proteopedia
Contents |
X-ray structure of EGFR in complex with oxime inhibitor
Template:ABSTRACT PUBMED 18508264
About this Structure
3bel is a 1 chain structure of Epidermal Growth Factor Receptor with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Xu G, Searle LL, Hughes TV, Beck AK, Connolly PJ, Abad MC, Neeper MP, Struble GT, Springer BA, Emanuel SL, Gruninger RH, Pandey N, Adams M, Moreno-Mazza S, Fuentes-Pesquera AR, Middleton SA, Greenberger LM. Discovery of novel 4-amino-6-arylaminopyrimidine-5-carbaldehyde oximes as dual inhibitors of EGFR and ErbB-2 protein tyrosine kinases. Bioorg Med Chem Lett. 2008 Jun 15;18(12):3495-9. Epub 2008 May 10. PMID:18508264 doi:http://dx.doi.org/10.1016/j.bmcl.2008.05.024
Categories: Homo sapiens | Receptor protein-tyrosine kinase | Abad, M C. | Connolly, P J. | Gaul, M D. | Neeper, M P. | Struble, G T. | Xu, G. | Alternative splicing | Anti-oncogene | Atp-binding | Cell cycle | Disease mutation | Glycoprotein | Kinase domain | Membrane | Nucleotide-binding | Phosphoprotein | Polymorphism | Receptor | Secreted | Transferase | Transmembrane | Tyrosine-protein kinase | Ubl conjugation
