2y3p

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Image:2y3p.jpg

Template:STRUCTURE 2y3p

CRYSTAL STRUCTURE OF N-TERMINAL DOMAIN OF GYRA WITH THE ANTIBIOTIC SIMOCYCLINONE D8

Template:ABSTRACT PUBMED 19965760

About this Structure

2y3p is a 2 chain structure with sequence from Escherichia coli. This structure supersedes the now removed PDB entry 2wl2. Full crystallographic information is available from OCA.

Reference

  • Edwards MJ, Flatman RH, Mitchenall LA, Stevenson CE, Le TB, Clarke TA, McKay AR, Fiedler HP, Buttner MJ, Lawson DM, Maxwell A. A crystal structure of the bifunctional antibiotic simocyclinone D8, bound to DNA gyrase. Science. 2009 Dec 4;326(5958):1415-8. PMID:19965760 doi:326/5958/1415
  • Edwards MJ, Flatman RH, Mitchenall LA, Stevenson CE, Maxwell A, Lawson DM. Crystallization and preliminary X-ray analysis of a complex formed between the antibiotic simocyclinone D8 and the DNA breakage-reunion domain of Escherichia coli DNA gyrase. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2009 Aug 1;65(Pt, 8):846-8. Epub 2009 Jul 30. PMID:19652356 doi:10.1107/S1744309109028097

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