3hmv

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Image:3hmv.png

Template:STRUCTURE 3hmv

Catalytic domain of human phosphodiesterase 4B2B in complex with a tetrahydrobenzothiophene inhibitor

Template:ABSTRACT PUBMED 19525117

About this Structure

3hmv is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Kranz M, Wall M, Evans B, Miah A, Ballantine S, Delves C, Dombroski B, Gross J, Schneck J, Villa JP, Neu M, Somers DO. Identification of PDE4B Over 4D subtype-selective inhibitors revealing an unprecedented binding mode. Bioorg Med Chem. 2009 Jul 15;17(14):5336-41. Epub 2009 Apr 5. PMID:19525117 doi:10.1016/j.bmc.2009.03.061

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