3l9m

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Template:STRUCTURE 3l9m

Crystal structure of PKAB3 (pka triple mutant V123A, L173M, Q181K) with compound 18

Template:ABSTRACT PUBMED 20137943

About this Structure

3l9m is a 4 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Zeng Q, Allen JG, Bourbeau MP, Wang X, Yao G, Tadesse S, Rider JT, Yuan CC, Hong FT, Lee MR, Zhang S, Lofgren JA, Freeman DJ, Yang S, Li C, Tominey E, Huang X, Hoffman D, Yamane HK, Fotsch C, Dominguez C, Hungate R, Zhang X. Azole-based inhibitors of AKT/PKB for the treatment of cancer. Bioorg Med Chem Lett. 2010 Mar 1;20(5):1559-64. Epub 2010 Jan 21. PMID:20137943 doi:10.1016/j.bmcl.2010.01.067

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