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3p7z

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Image:3p7z.png

Template:STRUCTURE 3p7z

Crystal structure of the Neurofibromin Sec14-PH module containing the patient derived mutation I1584V

Template:ABSTRACT PUBMED 21089070

About this Structure

3p7z is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

Welti S, Kuhn S, D'Angelo I, Bruugger B, Kaufmann D, Scheffzek K. Structural and biochemical consequences of NF1 associated non-truncating mutations in the Sec14-PH module of neurofibromin. Hum Mutat. 2010 Nov 18. PMID:21089070 doi:10.1002/humu.21405