3mjy

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Image:3mjy.jpg

Template:STRUCTURE 3mjy

Crystal structure of dihydroorotate dehydrogenase from Leishmania major in complex with 5-Aminoorotic acid

Template:ABSTRACT PUBMED 20965617

About this Structure

3mjy is a 2 chain structure with sequence from Thermomicrobium roseum. Full crystallographic information is available from OCA.

Reference

  • Cheleski J, Rocha JR, Pinheiro MP, Wiggers HJ, da Silva AB, Nonato MC, Montanari CA. Novel insights for dihydroorotate dehydrogenase class 1A inhibitors discovery. Eur J Med Chem. 2010 Dec;45(12):5899-909. Epub 2010 Oct 7. PMID:20965617 doi:10.1016/j.ejmech.2010.09.055

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