From Proteopedia

proteopedia linkproteopedia link

This Sandbox is Reserved from January 10, 2010, through April 10, 2011 for use in BCMB 307-Proteins course taught by Andrea Gorrell at the University of Northern British Columbia, Prince George, BC, Canada.

To get started: Click the edit this page tab at the top. Save the page after each step, then edit it again. Click the 3D button (when editing, above the wikitext box) to insert Jmol. show the Scene authoring tools, create a molecular scene, and save it. Copy the green link into the page. Add a description of your scene. Use the buttons above the wikitext box for bold, italics, links, headlines, etc. More help: Help:Editing

Thermolysin

Thermolysin is a protein that is isolated from the thermophile Bacillus thermoproteolyticus. ^[1] This protein is characterized by a remarkable stability under heat and protein denaturants. ^[2] The structure does not contain any stabilizing disulfide bonds.^[3] Instead, Thermolysin binds four calcium ions that are necessary for its thermal stability. ^[4] Ellen

spinqualitylabelsall models PDB ID 1q8k Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image
1q8k, 15 NMR models ()
Gene:	EIF2S1 OR EIF2A (Homo sapiens)
Structural annotation: Resources: CATH : 1Q8Ka02, 1Q8Ka01, 1Q8Ka03 InterPro : Ipr011488, Ipr003029, Ipr012340 Pfam : PF00575, PF07541 SCOP : d1q8ka1, d1q8ka2 UniProt : P05198
Functional annotation: Cellular component: cytoplasm polysome nucleus eukaryotic translation initiation factor 2 complex eukaryotic translation initiation factor 2B complex Biological process: translation regulation of translational initiation in response to stress regulation of translation Molecular function: RNA binding protein binding translation initiation factor activity
Evolutionary conservation: Toggle Conservation Colors: Rows = identical sequences: Further Information: Caveats, Explanation, Complete Results at ConSurfDB
Resources:	FirstGlance, OCA, RCSB, PDBsum
Coordinates:	save as pdb, mmCIF, xml

Works Cited

1. ↑ Matthews. (1988).
2. ↑ Vita et al., (1985).
3. ↑ Fontana et al., (1977).
4. ↑ Matthews. (1988).