2ivj
From Proteopedia
ISOPENICILLIN N SYNTHASE FROM ASPERGILLUS NIDULANS (ANAEROBIC AC-CYCLOPROPYLGLYCINE FE COMPLEX)
Template:ABSTRACT PUBMED 17397141
About this Structure
2ivj is a 1 chain structure with sequence from Emericella nidulans. Full crystallographic information is available from OCA.
Reference
- Howard-Jones AR, Elkins JM, Clifton IJ, Roach PL, Adlington RM, Baldwin JE, Rutledge PJ. Interactions of isopenicillin N synthase with cyclopropyl-containing substrate analogues reveal new mechanistic insight. Biochemistry. 2007 Apr 24;46(16):4755-62. Epub 2007 Mar 31. PMID:17397141 doi:10.1021/bi062314q
- Burzlaff NI, Rutledge PJ, Clifton IJ, Hensgens CM, Pickford M, Adlington RM, Roach PL, Baldwin JE. The reaction cycle of isopenicillin N synthase observed by X-ray diffraction. Nature. 1999 Oct 14;401(6754):721-4. PMID:10537113 doi:10.1038/44400
- Roach PL, Clifton IJ, Hensgens CM, Shibata N, Schofield CJ, Hajdu J, Baldwin JE. Structure of isopenicillin N synthase complexed with substrate and the mechanism of penicillin formation. Nature. 1997 Jun 19;387(6635):827-30. PMID:9194566 doi:http://dx.doi.org/10.1038/42990
Categories: Emericella nidulans | Isopenicillin-N synthase | Adlington, R M. | Baldwin, J E. | Clifton, I J. | Elkins, J M. | Howard-Jones, A R. | Roach, P L. | Rutledge, P J. | Antbiotic biosynthesis | Antibiotic biosynthesis | B-lactam antibiotic | Iron | Metal-binding | Oxidoreductase | Oxygenase | Penicillin biosynthesis | Vitamin c
