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1un5

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Revision as of 18:30, 14 March 2011 by OCA (Talk | contribs)
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Image:1un5.png

Template:STRUCTURE 1un5

ARH-II, AN ANGIOGENIN/RNASE A CHIMERA

Template:ABSTRACT PUBMED 14756559

About this Structure

1un5 is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Holloway DE, Chavali GB, Hares MC, Baker MD, Subbarao GV, Shapiro R, Acharya KR. Crystallographic studies on structural features that determine the enzymatic specificity and potency of human angiogenin: Thr44, Thr80, and residues 38-41. Biochemistry. 2004 Feb 10;43(5):1230-41. PMID:14756559 doi:10.1021/bi035654+
  • Leonidas DD, Shapiro R, Allen SC, Subbarao GV, Veluraja K, Acharya KR. Refined crystal structures of native human angiogenin and two active site variants: implications for the unique functional properties of an enzyme involved in neovascularisation during tumour growth. J Mol Biol. 1999 Jan 22;285(3):1209-33. PMID:9918722 doi:10.1006/jmbi.1998.2378
  • Harper JW, Fox EA, Shapiro R, Vallee BL. Mutagenesis of residues flanking Lys-40 enhances the enzymatic activity and reduces the angiogenic potency of angiogenin. Biochemistry. 1990 Aug 7;29(31):7297-302. PMID:1698454

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