1e0f
From Proteopedia
CRYSTAL STRUCTURE OF THE HUMAN ALPHA-THROMBIN-HAEMADIN COMPLEX: AN EXOSITE II-BINDING INHIBITOR
Template:ABSTRACT PUBMED 11060016
About this Structure
1e0f is a 9 chain structure with sequence from Haemadipsa sylvestris and Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Richardson JL, Kroger B, Hoeffken W, Sadler JE, Pereira P, Huber R, Bode W, Fuentes-Prior P. Crystal structure of the human alpha-thrombin-haemadin complex: an exosite II-binding inhibitor. EMBO J. 2000 Nov 1;19(21):5650-60. PMID:11060016 doi:10.1093/emboj/19.21.5650
- Strube KH, Kroger B, Bialojan S, Otte M, Dodt J. Isolation, sequence analysis, and cloning of haemadin. An anticoagulant peptide from the Indian leech. J Biol Chem. 1993 Apr 25;268(12):8590-5. PMID:8473305
- Bode W, Turk D, Karshikov A. The refined 1.9-A X-ray crystal structure of D-Phe-Pro-Arg chloromethylketone-inhibited human alpha-thrombin: structure analysis, overall structure, electrostatic properties, detailed active-site geometry, and structure-function relationships. Protein Sci. 1992 Apr;1(4):426-71. PMID:1304349