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1hkq

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Template:STRUCTURE 1hkq

PPS10 PLASMID DNA REPLICATION INITIATOR PROTEIN REPA. REPLICATION INACTIVE, DIMERIC N-TERMINAL DOMAIN.

About this Structure

1hkq is a 2 chain structure with sequence from Pseudomonas savastanoi. Full crystallographic information is available from OCA.

Reference

  • Forest KT, Filutowicz MS. Remodeling of replication initiator proteins. Nat Struct Biol. 2003 Jul;10(7):496-8. PMID:12825085 doi:10.1038/nsb0703-496
  • Diaz-Lopez T, Lages-Gonzalo M, Serrano-Lopez A, Alfonso C, Rivas G, Diaz-Orejas R, Giraldo R. Structural changes in RepA, a plasmid replication initiator, upon binding to origin DNA. J Biol Chem. 2003 May 16;278(20):18606-16. Epub 2003 Mar 7. PMID:12637554 doi:10.1074/jbc.M212024200
  • Giraldo R. Common domains in the initiators of DNA replication in Bacteria, Archaea and Eukarya: combined structural, functional and phylogenetic perspectives. FEMS Microbiol Rev. 2003 Jan;26(5):533-54. PMID:12586394
  • Giraldo R, Andreu JM, Diaz-Orejas R. Protein domains and conformational changes in the activation of RepA, a DNA replication initiator. EMBO J. 1998 Aug 3;17(15):4511-26. PMID:9687517 doi:10.1093/emboj/17.15.4511
  • Nieto C, Giraldo R, Fernandez-Tresguerres E, Diaz R. Genetic and functional analysis of the basic replicon of pPS10, a plasmid specific for Pseudomonas isolated from Pseudomonas syringae patovar savastanoi. J Mol Biol. 1992 Jan 20;223(2):415-26. PMID:1738155

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