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1qk5

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Image:1qk5.png

Template:STRUCTURE 1qk5

TOXOPLASMA GONDII HYPOXANTHINE-GUANINE PHOSPHORIBOSYLTRANSFERASE WITH XMP, PYROPHOSPHATE AND TWO MG2+ IONS

Template:ABSTRACT PUBMED 10545171

About this Structure

1qk5 is a 2 chain structure with sequence from Toxoplasma gondii. Full crystallographic information is available from OCA.

Reference

  • Heroux A, White EL, Ross LJ, Davis RL, Borhani DW. Crystal structure of Toxoplasma gondii hypoxanthine-guanine phosphoribosyltransferase with XMP, pyrophosphate, and two Mg(2+) ions bound: insights into the catalytic mechanism. Biochemistry. 1999 Nov 2;38(44):14495-506. PMID:10545171
  • Heroux A, White EL, Ross LJ, Borhani DW. Crystal structures of the Toxoplasma gondii hypoxanthine-guanine phosphoribosyltransferase-GMP and -IMP complexes: comparison of purine binding interactions with the XMP complex. Biochemistry. 1999 Nov 2;38(44):14485-94. PMID:10545170
  • Vasanthakumar G, van Ginkel S, Parish G. Isolation and sequencing of a cDNA encoding the hypoxanthine-guanine phosphoribosyltransferase from Toxoplasma gondii. Gene. 1994 Sep 15;147(1):153-4. PMID:8088544

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