2y3a

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Image:2y3a.jpg

Template:STRUCTURE 2y3a

CRYSTAL STRUCTURE OF P110BETA IN COMPLEX WITH ICSH2 OF P85BETA AND THE DRUG GDC-0941

Template:ABSTRACT PUBMED 21362552

About this Structure

2y3a is a 2 chain structure with sequence from Mus musculus. Full crystallographic information is available from OCA.

Reference

  • Zhang X, Vadas O, Perisic O, Anderson KE, Clark J, Hawkins PT, Stephens LR, Williams RL. Structure of Lipid Kinase p110beta/p85beta Elucidates an Unusual SH2-Domain-Mediated Inhibitory Mechanism. Mol Cell. 2011 Mar 4;41(5):567-78. PMID:21362552 doi:10.1016/j.molcel.2011.01.026

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