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2xnn
From Proteopedia
STRUCTURE OF NEK2 BOUND TO CCT242430
Template:ABSTRACT PUBMED 21366329
About this Structure
2xnn is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Solanki S, Innocenti P, Mas-Droux C, Boxall K, Barillari C, van Montfort RL, Aherne GW, Bayliss R, Hoelder S. Benzimidazole Inhibitors Induce a DFG-Out Conformation of Never in Mitosis Gene A-Related Kinase 2 (Nek2) without Binding to the Back Pocket and Reveal a Nonlinear Structure-Activity Relationship. J Med Chem. 2011 Mar 24;54(6):1626-39. Epub 2011 Mar 2. PMID:21366329 doi:10.1021/jm1011726
