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This Sandbox is Reserved from January 10, 2010, through April 10, 2011 for use in BCMB 307-Proteins course taught by Andrea Gorrell at the University of Northern British Columbia, Prince George, BC, Canada.

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spinqualitylabelsall models PDB ID 1kar Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image
1kar, resolution 2.10Å ()
Ligands:	,
Non-Standard Residues:
Gene:	HISD (Escherichia coli)
Activity:	Histidinol dehydrogenase, with EC number 1.1.1.23
Related:	1k75, 1kae, 1kah
Structural annotation: Resources: CATH : 1Kara02, 1Kara01, 1Karb01, 1Karb02 InterPro : Ipr012131, Ipr001692 Pfam : PF00815 SCOP : d1kara_, d1karb_ UniProt : P06988
Functional annotation: Biological process: histidine biosynthetic process amino acid biosynthetic process Molecular function: metal ion binding NAD binding histidinol dehydrogenase activity oxidoreductase activity zinc ion binding
Evolutionary conservation: Toggle Conservation Colors: Rows = identical sequences: Further Information: Caveats, Explanation, Complete Results at ConSurfDB
Resources:	FirstGlance, OCA, RCSB, PDBsum
Coordinates:	save as pdb, mmCIF, xml

Contents 1 My Protein of Interest (MPI) 1.1 Picture 1.2 Structure 1.3 Function 1.4 References

My Protein of Interest (MPI)

Basic information, current knowledge of areas found, etc.

Picture

Sec structure ^[1].

spinqualitylabelsall models Insert caption here Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image

^[1].

Structure

disulphides, secondary, etc. ^[2]

Function

evolutionary purpose?

References

1. ↑ ^{1.0 1.1} Barbosa JA, Sivaraman J, Li Y, Larocque R, Matte A, Schrag JD, Cygler M. Mechanism of action and NAD+-binding mode revealed by the crystal structure of L-histidinol dehydrogenase. Proc Natl Acad Sci U S A. 2002 Feb 19;99(4):1859-64. Epub 2002 Feb 12. PMID:11842181 doi:10.1073/pnas.022476199
2. ↑ Fallone CA. Epidemiology of the antibiotic resistance of Helicobacter pylori in Canada. Can J Gastroenterol. 2000 Nov;14(10):879-82. PMID:11111111