Ribosomal protein L25

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Image:1dfu.png
Crystal Structure of Ribosomal protein L25 1dfu

Template:STRUCTURE 1dfu

Ribosomal protein L25 (RPL25) is one of the 34 proteins which belong to the large 50S subunit of the prokaryotic ribosome or to the ca. 49 proteins in the large 60S subunit of the eukaryotic ribosome. Yeast RPL25 binds to 26S RRNA.

3D Structures of Ribosomal protein L25

RPL25

1b75 – EcRPL25 - Escherichia coli – NMR
1dfu – EcRPL25 + 5S RRNA fragment
1d6k - EcRPL25 + 5S RRNA fragment - NMR

L25 in 50S subunit+RNA

2xg0, 2xg2, 3kir, 3kit, 3kiw, 3kiy – TtRPL25 in 50S subunit+RNA fragments - Thermus thermophilus
2x9s, 2x9u, 3kni, 3knk, 3knm, 3kno, 2wrj, 2wrl, 2wro, 2wrr, 3hux, 3huz, 2wh2, 2wh4, 2wdi, 2wdj, 2wdl, 2wdn, 1vsp, 2v47 , 2v49, 1vsa, 2hgj, 2hgq, 2hgu, 2j01, 2j03, 1yl3, 3mrz, 3ms1, 3i8f, 3i8i, 3i9c, 3i9e, 3f1f, 3f1h, 3d5b, 3d5d, 1giy, 2y0v, 2y0x, 2y0z, 2y11, 2y13, 2y15, 2y17, 2y19, 3pyo, 3pyr, 3pyt, 3pyv, 2xtg, 2xux, 2xqe - TtRPL25 in 50S subunit+5S RRNA+23S RRNA
3fin - TtRPL25 in 50S subunit+5S RRNA+23S RRNA – Cryo-EM
2wwq – EcRPL25 in 50S subunit+5S RRNA+23S RRNA+mRNA+P-site tRNA
3i1n, 3i1p, 3i1r, 3i1t, 3i20, 3i22, 3e1b, 3e1d, 3df2, 3df4, 2vhn, 2qov, 2qox, 2i2t, 2i2v, 1vs6, 1vs8, 2aw4, 2awb, 3oas, 3oat, 3ofd, 3og0, 3ofq, 1vt2 - EcRPL25 in 50S subunit+5S RRNA+23S RRNA
3fik, 2gya, 2gyc, 3bbx, 1p85, 1p86 - EcRPL25 in 50S subunit+5S RRNA+23S RRNA – Cryo-EM
3kcr - EcRPL25 in 50S subunit+5S RRNA+23S RRNA+preprotein translocase
2zjq, 2zjr - DrRPL25 in 50S subunit+5S RRNA+23S RRNA – Deinococcus radiodurans

L25 in 50S subunit + antibiotics

3dll, 2zjp, 3cf5, 1xbp, 3pio, 3pip - DrRPL25 in 50S subunit+5S RRNA+23S RRNA+general stress protein Ctc+antibiotic
2qam, 2qao, 2qba, 2qbc, 2qoz, 2qp1, 3ofc, 3ofz, 3ofr, 3orb - EcRPL25 in 50S subunit+5S RRNA+23S RRNA+antibiotic
3oh5, 3oh7, 3ohj, 3ohk, 3ohz, 3oi1, 3oi3, 3oi5 - TtRPL25 in 50S subunit+5S RRNA+23S RRNA+antibiotic
1k73, 1kc8, 1k8a, 1k9m, 1kd1, 1m1k, 3cxc - HmRPL25P in 50S subunit+5S RRNA+23S RRNA+antibiotic

L25 in 50S subunit + ribosome releasing factor (RRF)

2qbe, 2qbg, 2qbi, 2qbk, 2z4l, 2z4n - EcRPL25 in 50S subunit+5S RRNA+23S RRNA+RRF
2rdo - EcRPL25 in 50S subunit+5S RRNA+23S RRNA+EF-G+RRF – Cryo-EM

L25 in 50S subunit + various proteins

2vhm - EcRPL25 in 50S subunit+5S RRNA+23S RRNA+PDF C-terminal helix
2j28 - EcRPL25 in 50S subunit+5S RRNA+23S RRNA+signal recognition particle – Cryo-EM

L25 in the 50S subunit

487d – EcRPL25 + RPL1 + RPL2 + RPL6 + RPL9 + RPL11 + RPL14 – Cryo-EM

L25 in the 60S subunit

3o5h, 3o58 - yRPL25 in 60S subunit+5S RRNA+25S RRNA+5.8S RRNA – yeast
1s1i - yRPL25 in 60S subunit+5S RRNA+5.8S RRNA – Cryo EM
3jyw – RPL25 in 60S subunit – Cryo EM – Thermomyces lanuginosus

L25 in large + small ribosomal subunit

1ml5 - EcRPL25 in 50S ribosomal subunit+30S ribosomal subunit+THX+chain release factor 2+P-site tRNA+tRNA Phe+mRNA fragment+23S RRNA+5S RRNA+16S RRNA – EM

L25 in part of 80S ribosome

2ww9, 2wwa – yRPL25+RPL4+RPL17+RPL19+RPL26+RPL31+RPL34+RPL35+RPL39+25S RRNA+SSH1P+SSS1+SEB2 – Cryo EM
2wwb - wRPL25+RPL4+RPL17+RPL19+RPL25+RPL26+RPL31+RPL35+RPL39+25S RRNA+5.8S RRNA+ dSEBC61 – Cryo EM

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Michal Harel, Alexander Berchansky, Joel L. Sussman

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