3k5v
From Proteopedia
Structure of Abl kinase in complex with imatinib and GNF-2
Template:ABSTRACT PUBMED 20072125
About this Structure
3k5v is a 2 chain structure with sequence from Mus musculus. Full crystallographic information is available from OCA.
Reference
- Zhang J, Adrian FJ, Jahnke W, Cowan-Jacob SW, Li AG, Iacob RE, Sim T, Powers J, Dierks C, Sun F, Guo GR, Ding Q, Okram B, Choi Y, Wojciechowski A, Deng X, Liu G, Fendrich G, Strauss A, Vajpai N, Grzesiek S, Tuntland T, Liu Y, Bursulaya B, Azam M, Manley PW, Engen JR, Daley GQ, Warmuth M, Gray NS. Targeting Bcr-Abl by combining allosteric with ATP-binding-site inhibitors. Nature. 2010 Jan 28;463(7280):501-6. Epub 2010 Jan 13. PMID:20072125 doi:10.1038/nature08675