3nax
From Proteopedia
PDK1 in complex with inhibitor MP7
Template:ABSTRACT PUBMED 21118801
About this Structure
3nax is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Nagashima K, Shumway SD, Sathyanarayanan S, Chen AH, Dolinski B, Xu Y, Keilhack H, Nguyen T, Wiznerowicz M, Li L, Lutterbach BA, Chi A, Paweletz C, Allison T, Yan Y, Munshi SK, Klippel A, Kraus M, Bobkova EV, Deshmukh S, Xu Z, Mueller U, Szewczak AA, Pan BS, Richon V, Pollock R, Blume-Jensen P, Northrup A, Andersen JN. Genetic and pharmacological inhibition of PDK1 in cancer cells: characterization of a selective allosteric kinase inhibitor. J Biol Chem. 2011 Feb 25;286(8):6433-48. Epub 2010 Nov 30. PMID:21118801 doi:10.1074/jbc.M110.156463
