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Phosphomannose mutase 2
Background
Phosphomannose mutase 2,
2amy. Phosphomannose mutase 2 is an cytosolic enzyme which is critical in the conversion of mannose-6-phosphate into mannose-1-phosphate. It's a homodimeric protein, having two identical subunits working as independent domains. It's a typical HAD superfamily protein, which has the characteristic "cap" and "core" domains.
How does PMM2 work?
Structure
