3orx

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Template:STRUCTURE 3orx

PDK1 mutant bound to allosteric disulfide fragment inhibitor 1F8

Template:ABSTRACT PUBMED 21430264

About this Structure

3orx is a 8 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Sadowsky JD, Burlingame MA, Wolan DW, McClendon CL, Jacobson MP, Wells JA. Turning a protein kinase on or off from a single allosteric site via disulfide trapping. Proc Natl Acad Sci U S A. 2011 Mar 23. PMID:21430264 doi:10.1073/pnas.1102376108

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