3pwr

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Image:3pwr.jpg

Template:STRUCTURE 3pwr

HIV-1 Protease Mutant L76V complexed with Saquinavir

Template:ABSTRACT PUBMED 21446746

About this Structure

3pwr is a 2 chain structure with sequence from Human immunodeficiency virus 1. Full crystallographic information is available from OCA.

Reference

  • Louis JM, Zhang Y, Sayer JM, Wang YF, Harrison RW, Weber IT. Drug Resistance Mutation L76V Decreases the Dimer Stability and Rate of Autoprocessing of HIV-1 Protease by Reducing Internal Hydrophobic Contacts. Biochemistry. 2011 Mar 29. PMID:21446746 doi:10.1021/bi200033z

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