3rhk

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Image:3rhk.jpg

Template:STRUCTURE 3rhk

Crystal structure of the catalytic domain of c-Met kinase in complex with ARQ 197

Template:ABSTRACT PUBMED 21454604

About this Structure

3rhk is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Eathiraj S, Palma R, Volckova E, Hirschi M, France DS, Ashwell MA, Chan TC. Discovery of a novel mode of protein kinase inhibition characterized by the mechanism of inhibition of human mesenchymal-epithelial transition factor (c-MET) autophosphorylation by ARQ 197. J Biol Chem. 2011 Mar 24. PMID:21454604 doi:10.1074/jbc.M110.213801

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OCA

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