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Aldehyde dehydrogenase

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Image:1nzx.png

Crystal Structure of Aldehyde dehydrogenase, 1nzx

Template:STRUCTURE 1nzx

Aldehyde dehydrogenase (ALDH) converts aldehydes to carboxylic acids while reducing NAD+ to NADH. In mammals there are 3 classes of ALDH and each contain constitutive and inducible forms. Class 1 is cytosolic; class 2 mitochondrial; class 3 found in tumors, stomach and cornea). ALDH family 7 member A1 is known as antiquitin and functions in the detoxification of aldehydes. Glyceraldehyde-3-phophate (G3P)-ALDH is called GAPDH.