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1a5a

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Image:1a5a.png

Template:STRUCTURE 1a5a

CRYO-CRYSTALLOGRAPHY OF A TRUE SUBSTRATE, INDOLE-3-GLYCEROL PHOSPHATE, BOUND TO A MUTANT (ALPHAD60N) TRYPTOPHAN SYNTHASE ALPHA2BETA2 COMPLEX REVEALS THE CORRECT ORIENTATION OF ACTIVE SITE ALPHA GLU 49

Template:ABSTRACT PUBMED 9535826

About this Structure

1a5a is a 2 chain structure with sequence from Salmonella enterica subsp. enterica serovar typhimurium. Full crystallographic information is available from OCA.

Reference

  • Rhee S, Miles EW, Davies DR. Cryo-crystallography of a true substrate, indole-3-glycerol phosphate, bound to a mutant (alphaD60N) tryptophan synthase alpha2beta2 complex reveals the correct orientation of active site alphaGlu49. J Biol Chem. 1998 Apr 10;273(15):8553-5. PMID:9535826
  • Rhee S, Miles EW, Mozzarelli A, Davies DR. Cryocrystallography and microspectrophotometry of a mutant (alpha D60N) tryptophan synthase alpha 2 beta 2 complex reveals allosteric roles of alpha Asp60. Biochemistry. 1998 Jul 28;37(30):10653-9. PMID:9692955 doi:10.1021/bi980779d

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