3k8t

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Image:3k8t.png

Template:STRUCTURE 3k8t

Structure of eukaryotic rnr large subunit R1 complexed with designed adp analog compound

Template:ABSTRACT PUBMED 19681093

About this Structure

3k8t is a 1 chain structure with sequence from Saccharomyces cerevisiae. Full crystallographic information is available from OCA.

Reference

  • Sun D, Xu H, Wijerathna SR, Dealwis C, Lee RE. Structure-Based Design, Synthesis, and Evaluation of 2'-(2-Hydroxyethyl)-2'-deoxyadenosine and the 5'-Diphosphate Derivative as Ribonucleotide Reductase Inhibitors. ChemMedChem. 2009 Oct;4(10):1649-56. PMID:19681093 doi:10.1002/cmdc.200900236

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