3lz6

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Template:STRUCTURE 3lz6

Guinea Pig 11beta hydroxysteroid dehydrogenase with PF-877423

Template:ABSTRACT PUBMED 20363126

About this Structure

3lz6 is a 4 chain structure with sequence from Cavia porcellus. Full crystallographic information is available from OCA.

Reference

  • Cheng H, Hoffman J, Le P, Nair SK, Cripps S, Matthews J, Smith C, Yang M, Kupchinsky S, Dress K, Edwards M, Cole B, Walters E, Loh C, Ermolieff J, Fanjul A, Bhat GB, Herrera J, Pauly T, Hosea N, Paderes G, Rejto P. The development and SAR of pyrrolidine carboxamide 11beta-HSD1 inhibitors. Bioorg Med Chem Lett. 2010 May 1;20(9):2897-902. Epub 2010 Mar 10. PMID:20363126 doi:10.1016/j.bmcl.2010.03.032

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