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3pz4

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Image:3pz4.jpg

Template:STRUCTURE 3pz4

Crystal structure of FTase(ALPHA-subunit; BETA-subunit DELTA C10) in complex with BMS3 and lipid substrate FPP

About this Structure

3pz4 is a 2 chain structure with sequence from Mus musculus. Full crystallographic information is available from OCA.

Reference

  • Bon RS, Guo Z, Stigter EA, Wetzel S, Menninger S, Wolf A, Choidas A, Alexandrov K, Blankenfeldt W, Goody RS, Waldmann H. Structure-Guided Development of Selective RabGGTase Inhibitors. Angew Chem Int Ed Engl. 2011 May 16;50(21):4957-61. doi:, 10.1002/anie.201101210. Epub 2011 Apr 21. PMID:21520375 doi:10.1002/anie.201101210

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