3mg6

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Template:STRUCTURE 3mg6

Structure of yeast 20S open-gate proteasome with Compound 6

Template:ABSTRACT PUBMED 20632995

About this Structure

3mg6 is a 28 chain structure with sequence from Saccharomyces cerevisiae. Full crystallographic information is available from OCA.

Reference

  • Blackburn C, Gigstad KM, Hales P, Garcia K, Jones M, Bruzzese FJ, Barrett C, Liu JX, Soucy TA, Sappal DS, Bump N, Olhava EJ, Fleming P, Dick LR, Tsu C, Sintchak MD, Blank JL. Characterization of a new series of non-covalent proteasome inhibitors with exquisite potency and selectivity for the 20S beta5-subunit. Biochem J. 2010 Aug 27;430(3):461-76. PMID:20632995 doi:10.1042/BJ20100383

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