3pwy

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Template:STRUCTURE 3pwy

Crystal structure of an extender (SPD28345)-modified human PDK1 complex 2

Template:ABSTRACT PUBMED 21459573

About this Structure

3pwy is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Erlanson DA, Arndt JW, Cancilla MT, Cao K, Elling RA, English N, Friedman J, Hansen SK, Hession C, Joseph I, Kumaravel G, Lee WC, Lind KE, McDowell RS, Miatkowski K, Nguyen C, Nguyen TB, Park S, Pathan N, Penny DM, Romanowski MJ, Scott D, Silvian L, Simmons RL, Tangonan BT, Yang W, Sun L. Discovery of a potent and highly selective PDK1 inhibitor via fragment-based drug discovery. Bioorg Med Chem Lett. 2011 Mar 17. PMID:21459573 doi:10.1016/j.bmcl.2011.03.032

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