3i65
From Proteopedia
Plasmodium falciparum dihydroorotate dehydrogenase bound with triazolopyrimidine-based inhibitor DSM1
Template:ABSTRACT PUBMED 19640844
About this Structure
3i65 is a 1 chain structure with sequence from Plasmodium falciparum 3d7. Full crystallographic information is available from OCA.
Reference
- Deng X, Gujjar R, El Mazouni F, Kaminsky W, Malmquist NA, Goldsmith EJ, Rathod PK, Phillips MA. Structural plasticity of malaria dihydroorotate dehydrogenase allows selective binding of diverse chemical scaffolds. J Biol Chem. 2009 Sep 25;284(39):26999-7009. Epub 2009 Jul 28. PMID:19640844 doi:10.1074/jbc.M109.028589
Categories: Dihydroorotate oxidase | Plasmodium falciparum 3d7 | Deng, X. | Phillips,M A. | Dihydroorotate dehydrogenase | Dsm1 | Fad | Flavoprotein | Inhibitor | Membrane | Mitochondrion | Mitochondrion inner membrane | Oxidoreductase | Plasmodium falciparum | Pyrimidine biosynthesis | Transit peptide | Triazolopyrimidine
