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3okj

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Image:3okj.jpg

Template:STRUCTURE 3okj

Alpha-keto-aldehyde binding mechanism reveals a novel lead structure motif for proteasome inhibition

About this Structure

3okj is a 28 chain structure with sequence from Saccharomyces cerevisiae. Full crystallographic information is available from OCA.

Reference

  • Grawert MA, Gallastegui N, Stein M, Schmidt B, Kloetzel PM, Huber R, Groll M. Elucidation of the alpha-keto-aldehyde binding mechanism: a lead structure motif for proteasome inhibition. Angew Chem Int Ed Engl. 2011 Jan 10;50(2):542-4. PMID:21154547 doi:10.1002/anie.201005488

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OCA

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