3rll

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Image:3rll.png

Template:STRUCTURE 3rll

Crystal structure of the T877A androgen receptor ligand binding domain in complex with (S)-N-(4-Cyano-3-(trifluoromethyl)phenyl)-3-(4-cyanonaphthalen-1-yloxy)-2-hydroxy-2-methylpropanamide

Template:ABSTRACT PUBMED 21506597

About this Structure

3rll is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Duke CB, Jones A, Bohl CE, Dalton JT, Miller DD. Unexpected Binding Orientation of Bulky-B-Ring Anti-Androgens and Implications for Future Drug Targets. J Med Chem. 2011 Apr 20. PMID:21506597 doi:10.1021/jm2000097

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OCA

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