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2wkz

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Image:2wkz.png

Template:STRUCTURE 2wkz

Contents

HIV-1 PROTEASE INHIBITORS CONTAINING A TERTIARY ALCOHOL IN THE TRANSITION-STATE MIMIC WITH IMPROVED CELL-BASED ANTIVIRAL ACTIVITY

Template:ABSTRACT PUBMED 19961222

About this Structure

2wkz is a 2 chain structure of Virus protease with sequence from Human immunodeficiency virus type 1 (isolate z2/cdc-z34 group m subtype d). Full crystallographic information is available from OCA.

See Also

Reference

  • Mahalingam AK, Axelsson L, Ekegren JK, Wannberg J, Kihlstrom J, Unge T, Wallberg H, Samuelsson B, Larhed M, Hallberg A. HIV-1 Protease Inhibitors with a Transition-State Mimic Comprising a Tertiary Alcohol: Improved Antiviral Activity in Cells. J Med Chem. 2009 Dec 4. PMID:19961222 doi:10.1021/jm901165g

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OCA

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