3qti

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Template:STRUCTURE 3qti

c-Met Kinase in Complex with NVP-BVU972

Template:ABSTRACT PUBMED 21697284

About this Structure

3qti is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Tiedt R, Degenkolbe E, Furet P, Appleton BA, Wagner S, Schoepfer J, Buck E, Ruddy D, Monahan JE, Jones MD, Blank J, Haasen D, Drueckes P, Wartmann M, McCarthy C, Sellers WR, Hofmann F. A drug resistance screen using a selective MET inhibitor reveals a spectrum of mutations that partially overlap with activating mutations found in cancer patients. Cancer Res. 2011 Jun 22. PMID:21697284 doi:10.1158/0008-5472.CAN-10-4433

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