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Group:MUZIC:CARP
From Proteopedia
Introduction
CARDIAC ANKYRIN REPEAT PROTEIN; CARPbelongs to the conserved muscle ankyrin repeat protein (MARP) family, Also known as Ankrd1.MARP family consist of two more homologous members Ankyrin repeat domain containing protein 2 (Ankrd2) and Diabetes related ankyrin repeat protein DARP.
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| 1n0r, resolution 1.50Å () | |||||||||
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| Ligands: | |||||||||
| Related: | 1n0q | ||||||||
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| Resources: | FirstGlance, OCA, PDBsum, RCSB | ||||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||||
Contents |
Structure
Using the N2A region of titin as bait in a yeast 2-hybrid screen of a skeletal muscle cDNA library cloned ANKRD1, which they called CARP. [1] full-length cDNA encoding ANKRD1 contains a nuclear localization signal, 4 tandem ankyrin-like repeats, multiple phosphorylation sites, and a PEST-rich region, which is typically found in rapidly degraded proteins.[2]
