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Mannosidase
From Proteopedia
Mannosidase (MAN) is an enzyme which hydrolyzes mannose. There are 2 kinds of MAN. αMAN which hydrolyzes α-mannose and βMAN.
3D structures of mannosidase
α-MAN
1hcu - αMAN – Trichoderma reesei
1o7d - αMAN – bovine
α-MAN class I
1fmi - hαMAN I - human
1fo2 - hαMAN I + deoxymannojirimycin
1fo3 - hαMAN I+ kifunensine
1dl2 - αMAN I catalytic domain + mannose - yeast
2ri8 - PcαMAN I + glycerol – Penicillium citrinum
1kre, 1kkt - PcαMAN I + mannose
1krf - PcαMAN I + kifunensine + mannose
1x9d - hαMAN I residues 243-699 + polysaccharide analog
1nxc - αMAN I + mannose – mouse
1g6i - αMAN I + deoxymannojirimycin
α-MAN class II
2wyh - SpαMAN II – Streptococcus pyrogenes
3bub, 1hty - DmαMAN II catalytic domain – Drosophila melanogaster
3bud - DmαMAN II catalytic domain (mutant)
3bui - DmαMAN II catalytic domain (mutant) + Tris
3bup, 3buq, 3czs - DmαMAN II catalytic domain (mutant) + mannose
3bvt, 3bvu, 3bvv, 3bvw, 3bvx - DmαMAN II catalytic domain (mutant) + mannopyranoside
1r33, 1r34 - DmαMAN II catalytic domain + mannopyranoside
3ddf, 3ddg, 2f18, 2f1a, 2f1b - DmαMAN II catalytic domain + pyrrolidin
2alw - DmαMAN II catalytic domain + noeuromycin
3cv5 - DmαMAN II catalytic domain + polysaccharide
3czn - DmαMAN II catalytic domain (mutant) + polysaccharide
2wyi - SpαMAN II + swainsonine
3blb, 1hww - DmαMAN II + swainsonine
3ejp, 3ejq, 3ejr, 3ejs, 3ejt, 3eju, 2ow6, 2ow7 - DmαMAN II catalytic domain + swainsonine analog
3dx0, 3dx2, 2f7o - DmαMAN II catalytic domain + mannostatine
3dx1, 3dx3, 3dx4, 2f7p - DmαMAN II catalytic domain + mannostatine analog
3d4y, 3d4z - DmαMAN II catalytic domain + imidazole derivative
3d50, 3d51, 3d52 - DmαMAN II catalytic domain + inhibitor
2fyv, 2f7q, 2f7r - DmαMAN II catalytic domain + amino-salacinol carboxylate analog
1tqv, 1tqw, 1tqs, 1tqt, 1tqu - DmαMAN II catalytic domain (mutant) + seleno-salacinol
1ps3 - DmαMAN II catalytic domain + kifunensine
1qwn - DmαMAN II catalytic domain + intermediate
1hxk - DmαMAN II catalytic domain + deoxymannojirimycin
1qwu - DmαMAN II catalytic domain (mutant) + guloside
1qx1 - DmαMAN II catalytic domain (mutant) + mannosyl
β-MAN
2je8 - BtβMAN residues 26-864 – Bacterioides thetaiotaomicron
2wbk - BtβMAN residues 26-864 + mannopyranoside
2vqt, 2vr4, 2vjx, 2vl4, 2vmf, 2vo5, 2vot, 2vqu - BtβMAN residues 26-864 + piperidine derivative
1oh4, 1of4 - TmβMAN catalytic domain + mannose
– Thermotoga maritima
1of3 - TmβMAN catalytic domain
