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2yh1

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Revision as of 04:57, 27 July 2011 by OCA (Talk | contribs)
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Image:2yh1.png

Template:STRUCTURE 2yh1

MODEL OF HUMAN U2AF65 TANDEM RRM1 AND RRM2 DOMAINS WITH EIGHT-SITE URIDINE BINDING

Template:ABSTRACT PUBMED 21753750

About this Structure

2yh1 is a 2 chain structure with sequence from Homo sapiens. Full experimental information is available from OCA.

Reference

  • Mackereth CD, Madl T, Bonnal S, Simon B, Zanier K, Gasch A, Rybin V, Valcarcel J, Sattler M. Multi-domain conformational selection underlies pre-mRNA splicing regulation by U2AF. Nature. 2011 Jul 13;475(7356):408-11. doi: 10.1038/nature10171. PMID:21753750 doi:10.1038/nature10171
  • Sickmier EA, Frato KE, Shen H, Paranawithana SR, Green MR, Kielkopf CL. Structural basis for polypyrimidine tract recognition by the essential pre-mRNA splicing factor U2AF65. Mol Cell. 2006 Jul 7;23(1):49-59. PMID:16818232 doi:http://dx.doi.org/10.1016/j.molcel.2006.05.025

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