2w2m
From Proteopedia
WT PCSK9-DELTAC BOUND TO WT EGF-A OF LDLR
Template:ABSTRACT PUBMED 19001363
About this Structure
2w2m is a 3 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Bottomley MJ, Cirillo A, Orsatti L, Ruggeri L, Fisher TS, Santoro JC, Cummings RT, Cubbon RM, Lo Surdo P, Calzetta A, Noto A, Baysarowich J, Mattu M, Talamo F, De Francesco R, Sparrow CP, Sitlani A, Carfi A. Structural and biochemical characterization of the wild type PCSK9-EGF(AB) complex and natural familial hypercholesterolemia mutants. J Biol Chem. 2009 Jan 9;284(2):1313-23. Epub 2008 Nov 10. PMID:19001363 doi:10.1074/jbc.M808363200
Categories: Homo sapiens | Baysarowich, J. | Bottomley, M J. | Calzetta, A. | Carfi, A. | Cirillo, A. | Cubbon, R M. | Cummings, R T. | Fisher, T S. | Francesco, R De. | Mattu, M. | Noto, A. | Orsatti, L. | Ruggeri, L. | Santoro, J C. | Sitlani, A. | Sparrow, C P. | Surdo, P Lo. | Talamo, F. | Cardiovascular disease | Familial hypercholesterolemia | Hydrolase-receptor complex | Lipid metabolism | Lipid transport | Serine protease | Steroid metabolism
